Document Type: Special Articles

Authors

1 Cardiology Resident, Department of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

2 Professor, Department of Neurology AND Iranian Neurological Research Center, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

3 Department of Cardiology AND Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

4 Department of Epidemiology and Biostatistics, School of Public Health AND Knowledge Utilization Research Center, Tehran University of Medical Sciences, Tehran, Iran

5 Endocrine and Metabolic Research Center, Obesity group, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Background: Migraine with aura (MA) has been identified as a risk factor for cardiovascular disease. Previous observation has also found higher prevalence of cardiovascular risk factors in migraineurs without aura (MO), but the results have been conflicting. The present study was conducted to assess the association between cardiovascular risk factors and migraine without aura among Iranians.Methods: In our study the prevalence of cardiovascular risk factors, including hypertension, hyperglycemia, dyslipidemia, obesity, cigarette smoking, and family history of early coronary artery disease, were studied in 347 migraineurs without aura and 267 non-migraineurs. The odds ratio (ORs) with 95% confidence interval (95% CI) was used to assess the strength of the association.Results:Patients with migraine without aura were at an increased risk of developing hypertension (ORadj = 1.9; P = 0.029), but there was no difference in other cardiovascular risk profiles, including hyperglycemia, dyslipidemia, obesity, cigarette smoking, and family history of early coronary artery disease.Conclusion: Our study revealed that the prevalence of hypertension was higher in migraineurs without aura in comparison with non-migraineurs. Therefore, physicians are supposed to be more vigilant in examining these patients and take care not to prescribe medications that may provoke hypertension.