Original Article
1. Validation of the Persian version of dysphagia in multiple sclerosis questionnaire for the assessment of dysphagia in multiple sclerosis

Zahra Jafari; Mohammad Rahim Shahbodaghi; Saman Maroufizadeh; Abdorreza Naser Moghadasi

Volume 17, Issue 3 , Summer 2018, Pages 99-104

Abstract
  Background: About one third of patients with multiple sclerosis (MS) experience dysphagia. Dysphagia can cause complications such as malnutrition, lung infections, aspiration pneumonia and dehydration, thus it is very helpful to diagnose dysphagia as soon as possible. The aim in this study was to translate ...  Read More

Original Article
2. Polymorphisms of serotonin transporter gene and psychological status in patients with multiple sclerosis

Shirin Farjadian; Bahareh Fakhraei; Zahra Niknam; Mahboubeh Nasiri; Aslan Azad; Mojtaba Farjam; Alireza Nikseresht

Volume 17, Issue 3 , Summer 2018, Pages 105-110

Abstract
  Background: Multiple sclerosis (MS) is the most common neuroinflammatory disease in young adults. Anxiety and depression may predispose individuals to MS and flare-ups. Serotonin transmission is modified in some brain regions of patients with MS, and these changes may contribute to their psychiatric ...  Read More

Original Article
3. The protective role of TBX21-1514T>C polymorphism in susceptibility to multiple sclerosis

Fatemeh Akbarian; Mitra Ataei; Zivar Salehi; Masoud Nabavi; Mohammad Hossein Sanati

Volume 17, Issue 3 , Summer 2018, Pages 111-116

Abstract
  Background: As a T-cell mediated disease, multiple sclerosis (MS) pathogenesis might be associated with the immune system and its involved genes. TBX21, which encodes T-bet transcription factor, is a critical regulator of the commitment to the Th1 lineage and Interferon gamma (IFNγ) production. Investigation ...  Read More

Original Article
4. Cognitive function, depression, and quality of life in patients with ruptured cerebral aneurysms

Samira Zabihyan; Seyed Javad Mousavi-Bayegi; Humain Baharvahdat; Farhad Faridhosseini; Payam Sasannejad; Maryam Salehi; Maryam Boroumand; Zahra Hatefipour

Volume 17, Issue 3 , Summer 2018, Pages 117-122

Abstract
  Background: Neuropsychiatric dysfunction is one of the most common complications after aneurysmal subarachnoid hemorrhage (aSAH). The aim of this study was to evaluate cognitive function, depression, and quality of life (QOL) in patients with aSAH. Methods: In this study, we prospectively enrolled patients ...  Read More

Original Article
5. Pegylated versus non-pegylated interferon beta 1a in patients with relapsing-remitting multiple sclerosis: A cost-effectiveness analysis

Amir Hashemi-Meshkini; Hedieh Sadat Zekri; Hasan Karimi-Yazdi; Pardis Zaboli; MohammadAli Sahraian; Shekoufeh Nikfar

Volume 17, Issue 3 , Summer 2018, Pages 123-128

Abstract
  Background: Pegylated (PEG) interferon beta 1a has been approved by the United States Food and Drug Administration (USFDA) as an alternative to interferon beta 1a for multiple sclerosis (MS). Due to its higher price, this study aimed to evaluate the cost-effectiveness of PEG-interferon beta 1-a compared ...  Read More

Review Article
6. Induction or aggravation of other immune-mediated disorders by disease-modifying therapy in treatment of multiple sclerosis

Seyed Mohammad Baghbanian; Mohammad Ali Sahraian

Volume 17, Issue 3 , Summer 2018, Pages 129-136

Abstract
  Interferon beta (IFN-β) and glatiramer acetate (GA) are the primary therapeutic immunomodulatory agents that interfere with relapsing-remitting multiple sclerosis (RRMS), and the most commonly-used drugs as well. Induction or aggravation of other immune-mediated diseases has been reported following ...  Read More

Review Article
7. Oxidative stress-related biomarkers in Parkinson’s disease: A systematic review and meta-analysis

Zeba Khan; Sharique Athar Ali

Volume 17, Issue 3 , Summer 2018, Pages 137-144

Abstract
  Parkinson’s disease (PD) is a neurodegenerative disease characterized with the loss of dopamine-producing neurons in a mid-brain. This loss is believed to be associated with number of environmental and genetic factors. Oxidative stress is found to be one of the factors responsible for the initiation ...  Read More

Short Communication
8. Transcranial sonography in carriers of Gaucher disease

Fatemeh Omrani; Shahla Ansari-Damavandi; Babak Zamani; Zahra Omrani; Nahid Mohammadzade; Sadra Rohani; Mohammad Rohani

Volume 17, Issue 3 , Summer 2018, Pages 145-148

Abstract
  Background: Glucocerebrosidase (GBA) mutation is the most common genetic risk factor in Parkinson’s disease (PD). Transcranial sonography (TCS) shows increased substantia nigra (SN) echogenicity in both idiopathic and genetic forms of PD. The goal of this study was to compare maximal area of SN hyperechogenicity ...  Read More

Short Communication
9. Hypothyroidism among patients with glioblastoma multiforme

Morteza Faghih-Jouybari; Soheil Naderi; Sara Mashayekhi; Tahereh Padeganeh

Volume 17, Issue 3 , Summer 2018, Pages 149-151

Abstract
  Background: Patients with glioblastoma multiforme (GBM) are prone to various metabolic changes such as hypothyroidism. The present study was planned to assess the frequency of hypothyroidism in these patients. Methods: Fifty-two patients with GBM were included. All of them had been treated by tumor ...  Read More