1. Electrophysiological studies in patients with seropositive/seronegative myasthenia gravis

Zahra Vahabi; Ferdos Nazari; Farzad Fatehi; Valiolah Bayegi; Zahra Saffarian; Fatemeh Saffarian; Shahriar Nafissi

Articles in Press, Accepted Manuscript, Available Online from 17 August 2021

  Background: Myasthenia gravis (MG) affects the neuromuscular transmission, causing fluctuating muscle weakness and fatigue. This study is carried out with the aim to study the electrophysiologic findings of different subtypes of MG referred to our center in Tehran, Iran. Methods: All patients with MG ...  Read More

2. Evaluation of quality of life and mood disorders in caregivers of patients with amyotrophic lateral sclerosis: A single-center cross-sectional study

Melika Rafiemehr; Ali Asghar Okhovat; Kamyar Moradi; Gilda Kiani Mehr; Shahriar Nafissi; Farzad Fatehi

Volume 19, Issue 4 , Autumn 2020, , Pages 190-195


  Background: Caregivers of patients with amyotrophic lateral sclerosis (ALS) may suffer from anxiety, depression, and reduced quality of life (QoL). Our goal was to evaluate the QoL and mood disorders in caregivers and their correlation with the patients' demographic, physical, and mental conditions. ...  Read More

3. Guillain-Barre syndrome in patients with coronavirus disease-2019: Report of six cases and review of literature

Ali Asghar Okhovat; Behnaz Ansari; Helia Hemasian; Bahram Haghi-Ashtiani; Soroor Advani; Bentolhoda Ziaadini; Siamak Abdi; Hajir Sikaroudi; Shahriar Nafissi; Farzad Fatehi

Volume 19, Issue 3 , Summer 2020, , Pages 122-130


  Background: Few studies have reported the association of Guillain-Barre syndrome (GBS) and coronavirus disease-2019 (COVID-19) infection. In this study, we reported GBS in six patients infected with COVID-19 and reviewed all existing literature about GBS in association with COVID-19. Methods: This study ...  Read More

4. Validation of Persian Individualized Neuromuscular Quality of Life in patients with muscular dystrophies

Kamyar Moradi; Shirin Jamal-Omidi; Maryam Masoudi; Sayna Bagheri; Shahriar Nafissi; Farzad Fatehi

Volume 19, Issue 1 , Winter 2020, , Pages 13-19


  Background: Neuromuscular disorders affect physical and mental aspects of a patient and in other words alter the patients’ quality of life (QOL). In the present study, we investigated the validity and reliability of the Persian version of Individualized Neuromuscular QOL (INQOL) to provide a better ...  Read More

5. An overview of motor unit number index reproducibility in amyotrophic lateral sclerosis

Davood Fathi; Shahriar Nafissi; Shahram Attarian; Christoph Neuwirth; Farzad Fatehi

Volume 18, Issue 3 , Summer 2019, , Pages 119-126

  Motor unit number index (MUNIX) is an electrophysiological technique to give an estimate of functioning motor neurons in a muscle. For any given neurophysiological technique for the use in clinical or research studies, reproducibility between different operators and in a single operator in different ...  Read More

6. Mutation analysis in exons 22 and 24 of SCN4A gene in Iranian patients with non-dystrophic myotonia

Mohammad Mehdi Heidari; Mehri Khatami; Shahriar Nafissi; Faezeh Hesami-Zokai; Afshin Khorrami

Volume 14, Issue 4 , Autumn 2015, , Pages 190-194

  Background: Non-dystrophic myotonias are a heterogeneous set of skeletal, muscular channelopathies, which have been associated with point mutations within sodium channel α-subunit (SCN4A) gene. Because exons 22 and 24 of SCN4A gene are recognized as hot spots for this disease, the purpose of the study ...  Read More

7. Observation of c.260A > G mutation in superoxide dismutase 1 that causes p.Asn86Ser in Iranian amyotrophic lateral sclerosis patient and absence of genotype/phenotype correlation

Marzieh Khani; Afagh Alavi; Shahriar Nafissi; Elahe Elahi

Volume 14, Issue 3 , Summer 2015, , Pages 152-157

  Background: Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disorder in European populations. ALS can be sporadic ALS (SALS) or familial ALS (FALS). Among 20 known ALS genes, mutations in C9orf72 and superoxide dismutase 1 (SOD1) are the most common genetic causes of the disease. ...  Read More

8. Comparison of electrophysiological findings in axonal and demyelinating Guillain-Barre syndrome.

Samira Yadegari; Shahriar Nafissi; Neda Kazemi

Volume 13, Issue 3 , Summer 2014, , Pages 138-143

  Background: Incidence and predominant subtype  of Guillain-Barre syndrome (GBS) differs geographically. Electrophysiology has an important  role in early diagnosis and  prediction  of prognosis. This study  is conducted to determine the frequent  subtype  of GBS in a large group of patients  ...  Read More

9. Dietary intake of nutrients and its correlation with fatigue in multiple sclerosis patients.

Sama Bitarafan; Mohammad-Hossein Harirchian; Shahriar Nafissi; Mohammad-Ali Sahraian; Mansoureh Togha; Fereydoun Siassi; Ahmad Saedisomeolia; Elham Alipour; Nakisa Mohammadpour; Maryam Chamary; Niyaz Mohammadzadeh Honarvar; Ali-Akbar Saboor-Yaraghi

Volume 13, Issue 1 , Winter 2014, , Pages 28-32

  Background:  The  role of nutrition  in the  progression  of multiple  sclerosis (MS) and  related  complications  such  as fatigue  has been  reported by several studies.  The  aim of this  study  is the  assessment of nutritional  status  and  its relationship with fatigue in multiple ...  Read More

10. Validation of the Persian version of the 40-item amyotrophic lateral sclerosis assessment questionnaire.

Hosein Shamshiri; Mohammad Reza Eshraghian; Nastaran Ameli; Shahriar Nafissi

Volume 12, Issue 3 , Summer 2013, , Pages 102-105

  Background: As a disease of motor nervous system (motor neuron  disease), amyotrophic  lateral  sclerosis (ALS)  has  a great  impact  on  several  aspects  of  quality  of  life (QoL). Generic questionnaires of QoL do not address all the especial features  of ALS and  therefore  translation  ...  Read More

11. Factors affecting bone mineral density in multiple sclerosis patients.

Azin Ayatollahi; Mohammad Reza Mohajeri-Tehrani; Shahriar Nafissi

Volume 12, Issue 1 , Winter 2013, , Pages 19-22

  Background: Multiple sclerosis (MS) is a demyelinating disease which can cause many disabilities for the patient. Recent data suggests that MS patients have higher risk for osteoporosis. This study was performed to investigate if the osteoporosis prevalence is higher in MS patients and to determine the ...  Read More

12. Four cases of brown-vialetto-van laere syndrome from Iran: Clinical and electrophysiologic findings.

Samira Yadegari; Askar Ghorbani; Mitra Ansari Dezfouli; Shahriar Nafissi

Volume 10, 3-4 , Autumn 2011, , Pages 54-7

  Brown-Vialetto-Van Laere syndrome (BVVLS) is a rare neurological disorder. We report our finding about four patients clinically and electrophysiologically diagnosed as BVVLS and denoted their clinical features with comparison to previous reports. The first symptom was bilateral hearing loss and the onset ...  Read More