Original Article
1. Comparison of the effects of low dose interferon and high dose interferon on reduction of the number and size of plaques in patients with Multiple Sclerosis: A historical cohort

Payam Khomand; Ghobad Moradi; Behrooz Ahsan; Setareh Abtahi

Volume 16, Issue 1 , Winter 2017, Pages 1-6

Abstract
  Background: This study was performed to compare the effects of low dose interferon beta-1 (IFN-β-1) (CinnoVex, 30 mcg) and high dose IFN-β-1 (REBIF, 44 mcg) on the reduction of the number and size of plaques in magnetic resonance imaging (MRI) in patients with multiple sclerosis (MS).Methods: This ...  Read More

Original Article
2. Awareness toward stroke in a population-based sample of Iranian adults

Mozaffar Hosseininezhad; Hannan Ebrahimi; Seyed Mohammad Seyedsaadat; Babak Bakhshayesh; Motahareh Asadi; Amir Reza Ghayeghran

Volume 16, Issue 1 , Winter 2017, Pages 7-14

Abstract
  Background: Stroke is the leading cause of death and functional disability. While there have been major advances regarding the management of stroke, a significant proportion of people are still unaware of stroke-related symptoms and risk factors. This study was performed to assess the awareness of stroke’s ...  Read More

Original Article
3. Circulating concentrations of interleukin (IL)-17 in patients with multiple sclerosis: Evaluation of the effects of gender, treatment, disease patterns and IL-23 receptor gene polymorphisms

Seyed Ali Ghaffari; Maryam Nemati; Hossain Hajghani; Hossainali Ebrahimi; Abdolkarim Sheikhi; Abdollah Jafarzadeh

Volume 16, Issue 1 , Winter 2017, Pages 15-25

Abstract
  Background: Interleukin (IL)-17/IL-23 axis performs a prominent role in the pathogenesis of several autoimmune disorders. This study aimed to investigate the concentrations of IL-17 in patients with multiple sclerosis (MS) and its relationship with gender, medication, disease forms and single nucleotide ...  Read More

Original Article
4. Knowledge, attitude, and practices among Iranian neurologists toward evidence-based medicine

Kaveh Shafiei; Fatemeh Sedaghati

Volume 16, Issue 1 , Winter 2017, Pages 26-29

Abstract
  Background: Evidence-based medicine (EBM) is a current practice in medicine to produce clinical practice guidelines from well-designed, randomized, controlled trials. We studied knowledge, attitude, and practice of EBM of neurologists who participated in the Iranian congress of neurology.Methods: A self-administered ...  Read More

Original Article
5. Polymorphisms at activated protein C cleavage sites of factor V: Are they important in the absence of factor V Leiden?

Ehsan Kheradmand; Shaghayegh Haghjooy-Javanmard; Leila Dehghani

Volume 16, Issue 1 , Winter 2017, Pages 30-33

Abstract
  Background: Activated protein C (APC) inactivates factor V (FV) by cleavage of its heavy chain at Arg306, Arg506, Arg679, and Lys994. Mutational changes, which abolish APC cleavage sites, may predispose thrombosis by altering the inactivation process of FV. FV Leiden (FVL) (Arg506Glu) has been demonstrated ...  Read More

Review Article
6. Multiple sclerosis-A disease on a dramatically rising trend in Iran: Review of possible reasons

Mohammad Ali Sahraian; Mohammad Sahebkar; Rouhollah Dehghani; Milad Derakhshan-Jazari; Vahid Kazami-Moghaddam; Ebrahim Kouchaki

Volume 16, Issue 1 , Winter 2017, Pages 34-40

Abstract
  There has been a global rising trend in recent years in the incidence of multiple sclerosis (MS). Despite being an MS low-risk region, this disease has also been recently on the rise in the Middle East. As part of the Middle East, Iran has not been spared either; however, the cause of this dramatic increase ...  Read More

12. Journal Index

Iranian journal of neurology Iranian journal of neurology

Volume 16, Issue 1 , Winter 2017

Abstract
  Official journal of Iranian Neurological Association  Read More