Document Type : Original Article
Authors
- Shahriar Faghani 1
- Ali Asghar Okhovat 2
- Narges Karimi 3
- Mana Moassefi 4
- Seyed Farzad Maroufi 5
- Shahriar Nafissi 1
- Farzad Fatehi 1
1 Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran Neuromuscular Research Center, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran Neuromuscular Research Center, Tehran University of Medical Sciences, Tehran, Iran Department of Neurology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
3 Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran Neuromuscular Research Center, Tehran University of Medical Sciences, Tehran, Iran Immunogenetics Research Center, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
4 Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
5 School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Abstract
Background: The 8-item myasthenia gravis activity of daily living (MG-ADL) questionnaire is a valid and reliable instrument for evaluating myasthenia gravis (MG)-associated disability. This study aims to assess its validity and reliability in the Iranian population.
Methods: A total number of 58 patients with MG were qualified for the examination. All 58 patients completed the Persian translation of 15-item Myasthenia Gravis Quality of Life (MG-QOL15) and MG-ADL questionnaires initially, and 30 filled out the MG-ADL questionnaire 2 to 4 weeks after the initial visit. Pearson correlation coefficient of questionnaires, internal consistency using Cronbach's alpha (α), and test-retest repeatability of the questionnaire were evaluated.
Results: The Pearson correlation coefficient of Persian versions of MG-QOL and MG-ADL was 0.93 (P < 0.01). The Persian MG-ADL showed satisfactory internal consistency (Cronbach’s α = 0.89) and test-retest reliability (r = 0.99, P < 0.01).
Conclusion: The Persian MG-ADL is a valid and reliable questionnaire for the determination of activities of daily life in Iranian patients with MG.
Keywords
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