Original Article
Cerebral border zone infarctions: An etiologic study

Mazyar Hashemilar; Parla Tohidi; Nasrin Forghani; Elyar Sadeghi-Hokmabadi; Ehsan Sharifipour

Volume 21, Issue 1 , January 2022, Pages 1-6


  Background: Cerebral border zone infarctions (BZIs) are a subtype of acute ischemic stroke that occur at the junction between two major cerebral arterial territories. Internal and external BZIs are defined based on the known patterns in brain magnetic resonance imaging (MRI). However, the etiology and ...  Read More

Original Article
A comparative study on the effectiveness of topiramate and propranolol in patients with migraine with aura

Seyed Ehsan Mohammadianinejad; Shahram Rafie; Saba Farashi

Volume 21, Issue 1 , January 2022, Pages 7-11


  Background: Migraine is considered as one of the most common and disabling diseases of the nervous system that has a great impact on quality of life (QOL) and a little risk of neurologic complications such as stroke. Migraine aura is known to be the result of cortical spreading depression and is associated ...  Read More

Original Article
Factors predisposing patients with temporal lobe epilepsy to seizure cluster

Marjan Asadollahi; Faezeh Maghsudloo; Leila Simani; Hossein Pakdaman

Volume 21, Issue 1 , January 2022, Pages 12-16


  Background: We aimed to identify the potential risk factors associated with seizure clusters in patients with temporal lobe epilepsy (TLE).Methods: This retrospective cross-sectional study was performed on all the consecutive patients with TLE, who were admitted to the Epilepsy Monitoring Unit (EMU), ...  Read More

Original Article
Assessment of computed tomography perfusion RAPID estimated core volume accuracy in patients following thrombectomy

Riwaj Bhagat; Allison Muha; Kerri Remmel; Wei Liu

Volume 21, Issue 1 , January 2022, Pages 17-22


  Background: Computed Tomography Perfusion (CTP) maps ischemic core volume (CV) and penumbra following a stroke; however, its accuracy in early symptom onset is not well studied. We compared the accuracy of CTP RAPID estimated CV with diffusion weighted imaging (DWI) infarct volume (IV) in patients following ...  Read More

Original Article
The prevalence and major determinants of non-compliance with anti-seizure medication among children

Ladan Afsharkhas; Shabnam Zamani; Azita Tavasoli; Babak Zamani; Atefeh Talebi

Volume 21, Issue 1 , January 2022, Pages 23-28


  Background: A wide range of adherence to the use of anti-seizure medications has been reported among children with the disease, and accordingly, various factors on the degree of adherence to the drug have been reported. But in our society, there is no clear picture of drug adherence and related factors ...  Read More

Original Article
Simultaneous screening for antibodies to myelin oligodendrocyte glycoprotein and aquaporin-4 in patients with optic neuritis using cell-based assay

Durgadevi Parthasarathy; Kulandai Lily Therese; Selvakumar Ambika; Selvi Krishnan; Durga Priyadarshini Santhakumar

Volume 21, Issue 1 , January 2022, Pages 29-34


  Background: This study was aimed to test simultaneous detection of antibodies to myelin oligodendrocyte glycoprotein (MOG)/aquaporin‑4 (AQP4) in serum samples of patients with clinically-diagnosed optic neuritis (ON), by fixed cell-based immunofluorescence assay (CBIFA).Methods: The study involved ...  Read More

Original Article
Validation of myasthenia gravis activity of daily living questionnaire: Persian version

Shahriar Faghani; Ali Asghar Okhovat; Narges Karimi; Mana Moassefi; Seyed Farzad Maroufi; Shahriar Nafissi; Farzad Fatehi

Volume 21, Issue 1 , January 2022, Pages 35-39


  Background: The 8-item myasthenia gravis activity of daily living (MG-ADL) questionnaire is a valid and reliable instrument for evaluating myasthenia gravis (MG)-associated disability. This study aims to assess its validity and reliability in the Iranian population.Methods: A total number of 58 patients ...  Read More

Review Article
Brain, heart, and sudden death

Shahram Oveisgharan; Fariborz Ghaffarpasand; Peter Sörös; Mustafa Toma; Nizal Sarrafzadegan; Vladimir Hachinski

Volume 21, Issue 1 , January 2022, Pages 40-51


  During the past 30 years, rate of coronary artery disease, as the main cause of sudden death, has decreased more than rate of sudden death. Likewise, cause of sudden death remains elusive in not a trivial portion of its victims. One possible reason is attention to only one organ, the heart, as the cause ...  Read More

Review Article
Diet and disease-related outcomes in multiple sclerosis: A systematic review of clinical trials

Mohammad Hossein Harirchian; Elmira Karimi; Sama Bitarafan

Volume 21, Issue 1 , January 2022, Pages 52-63


  Background: A growing number of clinical trials have investigated the role of diet in multiple sclerosis (MS) patients. We systematically reviewed the literature for clinical trials to assess the impact of different kinds of diets on MS-related outcomes.Methods: We searched MEDLINE, EMBASE, and Web of ...  Read More