Original Article
1. Association of cigarette smoking with neuromyelitis optica-immunoglobulin G sero-positivity in neuromyelitis optica spectrum disorder

Sharareh Eskandarieh; Abdorreza Naser Moghadasi; Mohammad Ali Sahraian; Amir Reza Azimi; Negar Molazadeh

Volume 18, Issue 3 , Summer 2019, Pages 93-98

Abstract
  Background: Neuromyelitis optica spectrum disorder (NMOSD) is a neuroinflammatory demyelinating disease caused by the presence of a highly specific serum autoantibody marker, NMO-immunoglobulin G (NMO-IgG), that reacts against the water channel aquaporin-4 (AQP4). The present study examined the association ...  Read More

Original Article
2. The effects of botulinum toxin type A injection on pain symptoms, quality of life, and sleep quality of patients with diabetic neuropathy: A randomized double-blind clinical trial

Hossein Salehi; Moein Moussaei; Zahra Kamiab; Alireza Vakilian

Volume 18, Issue 3 , Summer 2019, Pages 99-107

Abstract
  Background: Neuropathic pain is one of the most common problems in patients with diabetes mellitus (DM). In this study, the effect of botulinum toxin type A (BTX-A) on neuropathic pain, quality of sleep, and quality of life of diabetic patients with sensorimotor polyneuropathy was studied. Methods: ...  Read More

Original Article
3. Neuroprotective effect of dimethyl fumarate in stroke: The role of nuclear factor erythroid 2-related factor 2

Anahid Safari; Hamzeh Badeli-Sarkala; Mohammad Reza Namavar; Elias Kargar-Abarghoue; Neda Anssari; Sadegh Izadi; Afshin Borhani-Haghighi

Volume 18, Issue 3 , Summer 2019, Pages 108-113

Abstract
  Background: There is evidence that supports the neuroprotective effects of dimethyl fumarate (DMF) in stroke. Nuclear factor erythroid 2-related factor 2 (Nrf2) has both anti-oxidant and anti-inflammatory mechanisms. We investigated the neuroprotective effects of DMF via Nrf2 activation in the cortex, ...  Read More

Original Article
4. Association of 5-lipoxygenase activating protein gene polymorphism and stroke: A study from north east of Iran

Marjan Erfani; Ariane Sadr-Nabavi; Reza Jafarzadeh-Esfehani; Mohammad Shariati; Leila Ghanbari-Garekani; Samaneh Vojdani-Chahchaheh; Payam Sasannejad

Volume 18, Issue 3 , Summer 2019, Pages 114-118

Abstract
  Background: Stroke is a multifactorial disorder and a major cause of morbidity and mortality around the world. There are growing numbers of candidate gene pathways which are thought to be associated with stroke. Genes involved in lipid metabolism are important issues in stroke studies. Studying different ...  Read More

Review Article
5. An overview of motor unit number index reproducibility in amyotrophic lateral sclerosis

Davood Fathi; Shahriar Nafissi; Shahram Attarian; Christoph Neuwirth; Farzad Fatehi

Volume 18, Issue 3 , Summer 2019, Pages 119-126

Abstract
  Motor unit number index (MUNIX) is an electrophysiological technique to give an estimate of functioning motor neurons in a muscle. For any given neurophysiological technique for the use in clinical or research studies, reproducibility between different operators and in a single operator in different ...  Read More

Review Article
6. Role of dimethyl fumarate in the treatment of glioblastoma multiforme: A review article

Reza Ahmadi-Beni; Ali Najafi; Seyed Mehrdad Savar; Niayesh Mohebbi; Alireza Khoshnevisan

Volume 18, Issue 3 , Summer 2019, Pages 127-133

Abstract
  Glioblastoma multiforme (GBM), the most frequent malignant and aggressive primary brain tumor, is characterized by genetically unstable heterogeneous cells, diffused growth pattern, microvascular proliferation, and resistance to chemotherapy. Extensive investigations are being carried out to identify ...  Read More

Review Article
7. The trend of incidence and burden of neurological disease in Iran between 1990 and 2017: Based on global burden of disease estimations

Hedayat Abbastabar; Sama Bitarafan; Mohammad Hossein Harirchian

Volume 18, Issue 3 , Summer 2019, Pages 134-142

Abstract
  Neurological disease contributes significantly to morbidity and mortality in different ages and geographic areas around the world. The purpose of the current study was to investigate the incidence and disability-adjusted life years (DALYs) trend of neurological disease in Iran during 27 years ago. We ...  Read More